Guide Dogs of the Desert was founded in 1972 with the goal to provide quality guide dogs to the blind and the multi-handicapped blind. With the help of the Cathedral City Lions Club, Guide Dogs of the Desert was incorporated and licensed under California State Law and the Department of Consumer Affairs. By 1975 Guide Dogs of the Desert leased a two-bedroom house with a detached garage located on the current school property. In 1976, several individual members of Canyon Country Club in Palm Springs, California backed the purchase of the property and renovations commenced. The demand for specialized guide dog training and individualized instruction soon required larger facilities. In 1982, Lions Club members, local businesses and a grant from the Lions Club International Foundation served to expand the kennels and dormitory. The adjoining six acres was purchased to provide for future expansion. An additional five acres was purchased in 1995 for the development of a breeding facility and additional kennels. Student housing was completed in the fall of 1997, with accommodations for 12 students. The dormitory was designed with the input of students and graduates. The facility offers single bedrooms for each student with a shared bathroom for every two students. There is also an auditorium with a kitchen and a dining room. The dorm also has a recreation room equipped with a talking computer with Internet access, exercise equipment, musical instruments and a television. Microwaves and laundry equipment are also available. An additional kennel was built in 1998, made possible by the Mary Stuart Rogers Foundation. This facility is used strictly for the care of breeding dogs and their puppies.

Guide Dogs of the Desert provides custom trained guide dogs for safe mobility, loving companionship and life-enhancing independence to the blind.